Programme

Certosa di Pontignano

Monday, June 16th

14:00 – 19:00: GCD3 Registration

Sala Bracci – GCD3 opening

17:30 – 17:40: Opening Remarks: Welcome: Rector Prof. Di Pietra and Prof. Elena Petricci – University of Siena (Italy)
Chairman: Prof. Luigi Vaccaro
17:40 – 18:25: Dr. John C. Warner – Beyond Benign (USA): Noncovalent Derivatization: Improving performance AND sustainability through Green Chemistry
18:35 – 19:20: Prof. Klaus Kümmerer – University of Lüneburg (Germany): On the Path from Green Chemistry and Pharmacy to Sustainable Chemistry and Pharmacy

20:00 – 21:00: Dinner

Tuesday, June 17th

Sala Bracci 

Chairman: Prof. Darren Dixon
09:00 – 09:30: Prof. Yanlong Gu – Huazhong University and Technology (China): Strengthening the greenness of acid-catalyzed synthesis of fine chemicals
09:40 – 10:25: Prof. Michael Willis – University of Oxford (UK): New functional groups for synthetic and discovery chemistry
10:35 – 11:05: Prof. Jack L. Y. Chen – Auckland University of Technology (New Zealand): Modular assembly of biomimetic catalysts from amphiphilic precursors
11:15 – 11:30: Dr. Marco Ferrara – Flamma Group (Italy): Solvent Eco-Impact Metric: A Tool for Chemists to Drive Sustainability in Chemical Processes across Safety, Health, Waste, and Environmental Aspects

11:30 – 11:45: Coffee Break

Chairman: Prof. Elena Petricci
11:45 – 12:15: Prof. Walter Cabri – University of Bologna (Italy): Strategies and Tactics for a Sustainable Approach to Therapeutic Peptide
12:25 – 12:55: Prof. Margherita Brindisi – University of Naples “Federico II” (Italy): Intertwining continuous flow, mechanochemistry and paper-based platforms with the synthesis of pharmaceutically relevant compounds
13:05 – 13:20: Dr. Elena Tomarelli – University of Perugia (Italy): Sulfation Unleashed: An Innovative Biocatalytic Approach to Organosulfates

13:20 – 14:20: Lunch

14:20 – 15:20: Poster session
Chairman: Prof. Margherita Brindisi
15:20 – 16:05: Prof. Stephen Fletcher – University of Oxford (UK): Controlling Regioselectivity in Catalytic Asymmetric Suzuki-type Reaction
16:15 – 16:30: Ms. Suzanne Davison – University of Oxford (UK): New Aza-Sulfur Compounds to Explore Chemical Space
16:30 – 16:45: Ms. Bianca Martinengo – University of Bologna (Italy): Harnessing Cashew Nutshell Liquid as a Sustainable Source for Antiparasitic Drug Development

16:45 – 17:00: Coffee Break

17:00 – 17:15: Mr. Nicholas D. D’Arcy-Evans – University of Oxford (UK): Methylene Deletion from Lactams and Amides
17:15 – 17:30: Dr. Stefano Giovanninetti – Stepbio (Italy): New Tools for development studies of greener chemical processes
17:30 – 19:00: “Green Chemistry” round table (organised by the Royal Society of Chemistry)

19:30 – 21:00: Dinner

21:00: Ice Cream & Gin (sponsored by TCI)

Wednesday, June 18th

Sala Bracci 

Chairman: Prof. Michael Willis
09:00 – 09:45: Dr. Patrizio Mattei – Roche (Switzerland): The discovery and early development of Zosurabalpin
09:55 – 10:40: Dr. Luigi Stasi – UCB (UK): Discovery and in vivo characterization of benzimidazole based IL-17 inhibitors
10:50 – 11:05: Ms. Annalisa Fanizzi – University of Bari “Aldo Moro” (Italy): Rational optimization of the N-adamantyl-anthranil amide structural core for the development of new selective ligands for the Cannabinoid subtype 2 Receptor (CB2R)

11:05 – 11:20: Coffee Break

Chairman: Prof. Filippo Minutolo
11:20 – 12:05: Dr. Werngard Czechtizky – AstraZeneca (Sweden): New Chemistries, Predictive Modeling & Greener Labs to reduce AZ´s Carbon Footprint
12:15 – 13:00: Dr. Michael K. Jensen – Biomia (Denmark): Nature-inspired drug discovery and scalable manufacturing using biotechnology
13:10 – 13:40: Dr. Serena Meini – Axxam (Italy): Building the Ideal Screening Collection: Innovation and Strategy in High-Throughput Screening

13:40 – 14:40: Lunch

Chairman: Prof. Marco L. Lolli
14:40 – 15:25: Dr. Vincent Bordas – Novartis Institutes for BioMedical Research (Switzerland): The Discovery and Synthesis of IAG933 A YAP/TEAD inhibitor for solid tumor indications
15:35 – 15:50: Ms. Alessia A. Corallo – University of Siena (Italy): New CB2 dualsteric ligands for the treatment of multiple sclerosis
Teamwork Session
15:50 – 16:50: Symeres – Axxam teamwork

16:50 – 17:05: Coffee Break

17:05 – 18:05: Symeres – Axxam teamwork

19:15: Bus departure from Certosa di Pontignano to Piazza Gramsci (Siena)
20:30: Social Dinner in Piazza del Campo (Siena)

Thursday, June 19th

Sala Bracci 

Chairman: Prof. Antimo Gioiello
09:00 – 09:30: Dr. Francesca Micoli – GSK Vaccine Institute for Global Health (Italy): Development of vaccines for low and middle income countries
09:40 – 09:55: Dr. Ermal Ismalaj – CIC-biomiaGUNE (Spain): PET Imaging of Novel Biomarkers: Targeting L-Type Calcium Channels In Vivo
09:55 – 10:10: Dr. Dario Gentili – University of Camerino (Italy): The Influence of Side Chains in Alkenyl Resorcinol Derivatives
10:10 – 10:25: Ms. Arianna Ghelardi – University of Pisa (Italy): Searching new pharmaceutical dual-drug solid systems by combining solvent-based crystallization, mechanochemistry and solid-state NMR spectroscopy
10:25 – 10:30: Ms. Federica Oleari – University of Genoa (Italy): Design and Synthesis of Triazine Derivatives as Potential SIRT2 Inhibitors: A Molecular Simplification Approach
10:30 – 10:35: Ms. Maryam Saeb Fotohieh – University of Bari “Aldo Moro” (Italy): Sustainable Hydrogen Borrowing Catalysis in Deep Eutectic Solvents; Towards Greener C-N Bond Formation
10:35 – 10:40: Dr. Matteo Bartalucci – University of Perugia (Italy): A combined microwave and continuous flow approach for iodination of anilines and their consecutive use in Heck cross-coupling reaction
10:40 – 10:45: Ms. Elena Graziano – University of Bari “Aldo Moro” (Italy): Generation and Use of Bicyclo[1.1.0]butyllithium Under Continuous Flow Conditions
10:45 – 10:50: Ms. Iqra Munir – University of Camerino (Italy): A new Microwave Assisted Organic Synthesis of polysubstituted benzene
10:50 – 10:55: Mr. Salvatore Mottola – University of Campania “Luigi Vanvitelli” (Italy): Sustainable Ultrasound-Assisted Solid-Phase peptide synthesis (SUS-SPPS): Less Waste, more efficiency
10:55 – 11:00: Flash presentation of a selected poster
11:00 – 11:05: Flash presentation of a selected poster
11:05 – 11:10: Flash presentation of a selected poster

11:10 – 11:25: Coffee Break

11:25 – 11:40: Best Poster and Best Teamwork awards from the Royal Society of Chemistry
11:40 – 12:25: Closing Lecture: Dr. Russel Thomas – Symeres (The Netherlands): 21st Century drug discovery: challenges (and maybe some solutions)
12:35 – 12:50: Closing Remarks: Prof. Elena Petricci – University of Siena (Italy)

12:50: Lunch